Donald is portrayed by Hal Sparks.
Donald is a scientist and inventor who created the bionic super humans, known as the "Lab Rats." When he married Leo's mother,Tasha, they moved into his home that he bought with the money he got from inventing things for the government. Leo, his step son, accidentally discovered his secret lair where he kept his super humans. He is also seen to be very full of himself and proud of his inventions, even if something goes wrong, as seen in Rats on a Train. He claims to be 38 years old, but the lab rats and Leo don't believe him.
Donald commonly appears eccentric, over the top, childish and very arrogant. He is well aware of his large ego, but thinks he has every right to have one. Although arrogant, Donald is a genuinely nice person, who strongly cares about others and has a strict moral constitution, something he's implemented on Adam, Bree and Chase, it being him who raised them. Although he raised them, Donald's relationship is closer to an employer and employees than a father to his children, despite this he cares deeply about them, and will rush to their aid when ever they are in trouble. Although eccentric and at times wacky, Donald also knows when its time to be responsible and mature, and will always be ready for emergencies (not that he doesn't panic). Donald's arrogance can at times work against him, as he can be overly confident and unwilling to admit his failings. He's also always ready to remind others of the severity of the situation and the bigger picture. Although at times he can be uncaring, selfish and greedy, most of the time Donald is a genuinely nice and kindhearted man, who loves his wife and cares deeply for Leo, seeing him as a son.
Tasha is Donald's wife and the mother of Leo. Tasha is motherly figure to Leo (of course, he's her son) and also Adam, Bree, and Chase, but mainly Bree because she's the only other girl. It is revealed in the first episode (Crash, Chop and Burn) that Tasha was a rebellious teenagerbecause she said that on night she and her friend Viona Miclejohn snuck out and crashed a party. Although he two do have disputes, he does love Tasha, and will go to her defense when she needs him, for instant when Eddie antagonizes her.
Leo is Donald's teen stepson. He mainly calls him Big D. Mainly because of his position as head of the Davenport Household. He also wants to be bionic and go on missions with Adam, Bree, and Chase. He snuck onto a mission in Rats on a Train. Mr. Davenport sometimes tries too hard to bond with Leo.
Chase is Donald's adoptive son/youngest super intelligent and caring bionic nephew. He seems to like Chase the most because they bond over their intelligence and knowledge of technology. However, in Rats on a Train he says he liked Chase better when he was frozen. He also appears to be closest with Chase as he always did 'The Call" with him (although that was probably partially because Chase is smart). He also always makes Chase the leader on missions and thus has the highest expectations towards Chase. He has the strongest bond with Chase. In the episode "Hole In One" the others wanted Chase to take the blame and claimed that "they all know he's his favorite". However, in Bionic Showdown Chase was the first to question Donald's orders and the first to mock him.
Adam is Donald's adoptive son/oldest super strong bionic teen nephew. Although sometimes disturbed by Adam's stupidity, he still cares for him and tries to bond with him at times (he tried watching Pig Zombies with him but Adam was scared of them).
Bree is Donald's adoptive daughter/super fast bionic teen niece. Donald is over-protective of her and really cares for her. When Bree made him realize that he always spends time with Adam and Chase, he felt bad and did something with her instead.
Rose is Donald's mother-in-law. He and Rose aren't that close but can tolerate each other.
Eddy is Donald's smart home system. It is sarcastic, deceitful, and selfish. It is also slightly self-absorbed like Donald. Although Donald says he's 'vaguely disturbing', he and Eddy are friends and according to Tasha, Donald's best friend. Eddy hates every member of the Davenport household except Donald. He especially hates Tasha who Eddy thinks has taken Donald from him. Sometimes, they play games together, such as dodge ball. However, Eddy cheats.
- Intelligence: Donald is a undeniable genius, able to make revolutionary technology with ease, his knowledge is incredible, only matched by his engineering skills, as as well as working out how to make his contraptions, he is also equally able to build them. He is the only character who appears brighter thanChase.
- Martial Arts: He is highly capable of hand to hand combat as shown in "Bionic Birthday Fail" and "Quarantined," as he is the one who trained Adam, Bree and Chase in hand to hand combat, and is even able to take them on, despite them being Bionically enhanced.
- Bravery: Donald is a very brave man, although a normal human, he is more than willing to put himself in dangerous situations when the need is necessary, he will often come through and help Adam, Bree, and Chase if they require help on their mission.
- Simplicity: His biggest weakness. Although an overwhelmingly intelligent and innovative thinker, it is this same genius level intellect that seems to be a problem as he is unable or simply cannot think simplistically. Seen in Missin' the Mission when he believed that he could contain the gas without Adam, Bree and Chase until Leo made him realize that they could use the fan as an alternative. He thinks in complexity.
- Technology: Donald cannot go a day without technology, he could not even relax at the beach with Tasha. He even made a cellphone can to try and find out about the mission which didn't work because Tasha caught Leo drinking "cola".
- Over-inventing things: As seen in Night Of The Living Virus, he invents too many things unnecessarily such as a secret laser system.
- Arrogance: Donald is very arrogant, and at times seems to be a borderline egomaniac. Although most of the time he simply appears harmlessly eccentric, at times he can be greedy, selfish and mean. His arrogance also creates other problems, such as him being unwilling to admit he was wrong, or except responsibility for his mistakes and failings. A very notable example is in The Rats Strike Back were he refuses to admit he was wrong to the very last minute, causing him to lose an important contract. He even admits he has a colossal ego on occasion, such as describing Adam's monster truck as "a car the same size as my ego."
- Thinking Quick Although he is incredibly intelligent, he has difficulty thinking on his feet when worried or nervous. He sometimes comes to a loss of words and need people to help him. In Mission: Space, Donald asks for Leo's help when Marcus finds the lab and inquires about the capsule.
- Selfishness: At times Donald can be incredibly selfish, and sometimes acts like he can do anything he wants purely because he is rich and a genius, at times he only thinks of money and himself.
- He is a billionaire.
- His room has video games, action figures, and a 50 ft TV screen. 
- He invented a virtual, holographic 3D TV.
- He invented a cyber mask.
- Eddy calls him "Donny".
- He's a very wealthy scientist.
- His bionic children always call him "Mr. Davenport" but still regard him as their father.
- Despite inventing Eddy, he finds him as a 'vaguely disturbing smart-home system'.
- Leo calls him "Big D".
- He created the world's fastest train and helicopter. 
- Had action figures as friends during his childhood.
- He calls his action figure friends pieces of his heart.
- His last name Davenport is also the same name as the Presidential family in The First Kid a movie made by Disney.
- He has never told Adam, Bree, or Chase about Santa.
- He has never celebrated Adam's, Bree's, or Chase's birthdays. (Bionic Birthday Fail)
- He celebrates with cookies.
- In the alternate future, he became morbidly-obese and bald. Leo questioned how he could become bald with all the proven over the counter hair treatments available.
- It was revealed in "Can I Borrow the Helicopter?," that Davenport has a pool table room, a bumper car room, an arcade room, a surf simulator room, and a room full of mirrors that Davenport likes to call "a room full of me".
- He gets over-excited when he has "Father-Son Times" with Leo.
- He used the word Leo-it-up in Memory wipe
- He is on "The Call".
- He tends to wear dark or dull colors like black, grey, brown etc.
- Chase is his best martial arts student as he was the only one who could put up a fight against him (Bionic Birthday Fail). Chase also took out more bad guys than Adam using martial arts (Quarantined).
- He likes to watch Pig Zombie movies.
- He invented a car that drives itself.
- He said that money is not as important as Adam, Bree and Chase (but is a very close second).
- In Quarantined, Adam was convinced he was a 'space witch', "..the worst kind".
- His nickname, Big D, is the same nickname as Dallas, Texas, USA.
- He described high school as "soul crushing".
- He has an art vault, complete with multiple copies of famous paintings with his own face painted on it, which he calls Daven-Portraits.
- Chase, while trying to get Davenport away from the ruined painting, said that he should do a "Daven-Sculpture", which greatly intrigued him. It is still unknown if any Daven-Sculptures have been completed.
- He sings his own elevator music.
- His high school sport was A.P. Chemistry.
- Douglas is his younger brother.
- He believed, along with the FBI & his mom, that Douglas was dead.
- Douglas calls him "Donny," which he hates to be called. Although, when Eddie calls him that, he sometimes doesn't mind.
- Not only did he create Eddy, but he also created Edie.
- He was once in an a Capella group made entirely up of boys, which Douglas refers to as a 'boy band'.
- When Eddy said to him "Daddy's home!" he found it creepy.
- Donald is currently (approximately) 38-39 years old.
- His catch phrase is "I'm awesome!"
- He's been in Davenport Industries since 1992 (Twas The Mission Before Christmas).